付华林 助理研究员
发表时间:2017-03-08 阅读次数:94次
 

付华林, 助理研究员

2006年,博士毕业于美国南加州大学(USC)生化和分子生物学专业,在南加州大学期间构建了Msx1 和Msx2 Cre/LoxP条件性基因敲除小鼠。2007年至2009年在美国加州大学洛杉矶分校(UCLA)胰岛研究中心进行博士后训练,构建了三种和胰岛细胞发育相关的转基因小鼠品系包括Dox可诱导的EZH2转基因小鼠。2009年11月回国聘为上海交通大学系统生物医学研究院助理研究员,主要进行大片段基因剔除小鼠品系的培育和神经发育的研究。2012年1月至今,转到微纳科学技术研究院,主要从事胃癌标志物,胃幽门螺旋杆菌CagA致癌机制,胃癌肿瘤5hmcDNA修饰表观遗传和纳米生物学的相关研究。


发表相关论文:
1,Ma Y, Mi YJ, Dai YK, Fu HL, Cui DX, Jin WL. The Inverse F-BAR Domain Protein srGAP2 Acts through srGAP3 to Modulate Neuronal Differentiation and Neurite Outgrowth of Mouse Neuroblastoma Cells. PLoS One. 2013;8(3):e57865. doi: 10.1371/journal.pone.0057865. Epub 2013 Mar 7.
2,Chen J, Wang W, Zhang T, Ji J, Qian Q, Lu L, Fu H, Jin W, Cui D. Differential expression of phospholipase C epsilon 1 is associated with chronic atrophic gastritis and gastric cancer. PLoS One. 2012;7(10):e47563. Epub 2012 Oct 15
3,Ruan J, Song H, Li C, Bao C, Fu H, Wang K, Ni J, Cui D. DiR-labeled Embryonic Stem Cells for Targeted Imaging of in vivo Gastric Cancer Cells. Theranostics. 2012;2(6):618-28. Epub 2012 Jun 15.
4,Chen K, Mi YJ, Ma Y, Fu HL, Jin WL. The mental retardation associated protein, srGAP3 negatively regulates VPA-induced neuronal differentiation of Neuro 2A cells. Cell Mol Neurobiol.  2011 Jul; 31 (5):675-86
5,Qi L, Wu L, Zheng S, Wang Y, Fu H, Cui D. Cell-Penetrating Magnetic Nanoparticles for Highly Efficient Delivery and Intracellular Imaging of siRNA. Biomacromolecules. 2012 Sep 10;13(9):2723-30. Epub 2012 Aug 31.
6,Hualin Fu, Ishii Mamoru, Gu Ying, Robert Maxson. Conditional alleles of Msx1 and Msx2 . Genesis 2007 Aug; 45(8): 477-814,
7,Hualin Fu. What is the material base of acupuncture? The nerves! Medical Hypothesis 2000 Mar; 54(3) 358-9

专利:
US7662549: Methylation Altered DNA Sequences as Markers Associated with Human Cancer. Markl Isabel, Jones Peter A, Tomigahara Yoshitaka, Liang Gangning, Fu Hualin, Chen Jonathan  Feb 16, 2010


联系方式
上海市东川路800号 上海交通大学 微纳科学技术研究院
E-mail:hfu@sjtu.edu.cn   

 

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